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甲基化精氨酸單甲基精氨酸(MMA),非對(duì)稱二甲基精氨酸(ADMA)和對(duì)稱二甲基精氨酸(SDMA)

作為Covalab全國(guó)總代理,艾美捷科技強(qiáng)烈推薦Covalab熱銷產(chǎn)品甲基化精氨酸抗體(7E6)。產(chǎn)品僅用于科研,不可用于臨床診斷。
| 產(chǎn)品名稱 | 貨號(hào) | 詳情 |
| 甲基化精氨酸抗體(7E6) | mab0002-P-100ug | 查看 |
甲基化精氨酸抗體(7E6):
| ID Covalab | mab0002-P |
|---|---|
| 產(chǎn)品類型 | 一抗 |
| 克隆性 | 單克隆抗體 |
| 克隆 | (7E6) |
| 同種型 | 免疫球蛋白G1 / 卡帕 |
| 在 | 鼠 |
| 免疫原 | 改性甲基精氨酸 |
| 活叉反應(yīng) | 與甲基化精氨酸的所有結(jié)構(gòu)發(fā)生反應(yīng),包括游離和結(jié)合。與游離和結(jié)合的NG - 單甲基精氨酸交叉反應(yīng)。與游離或結(jié)合的精氨酸無(wú)交叉反應(yīng)。修復(fù)補(bǔ)碼的能力:未知 |
| 物種 | 所有 SP. |
| 標(biāo)簽 | 沒(méi)有 |
| 形式 | 純化(蛋白A) |
| 防腐劑 | 沒(méi)有 |
| 存儲(chǔ)說(shuō)明 | 凍干粉末在-2°C下穩(wěn)定至少20年.在+4°C下儲(chǔ)存重組抗體.長(zhǎng)時(shí)間在-20°C 下分裝儲(chǔ)存. 抗體自收到之日起保證6個(gè)月。 |
| 目標(biāo) | 甲基化精氨酸單甲基精氨酸(MMA),非對(duì)稱二甲基精氨酸(ADMA)和對(duì)稱二甲基精氨酸(SDMA) |
| 應(yīng)用 | ChIP, ELISA, IP, WB |
| 工作稀釋液 | 最佳稀釋度應(yīng)由最終用戶確定。 以下僅供參考:- ChIP : 1/100 至 1/10 000 - WB : 1/500 至 1/5 000 |
文獻(xiàn)參考:
* SR Green. Regulation of Citric Acid Cycle Enzymes and Related Pathways in the Skeletal Muscle of Hibernating Richardson’s Ground Squirrels, Urocitellus Richardsonii. Thesis Nov 2021 (WB)
* SR Green et al. BBA - Proteins and Proteomics. 2020 May 20
* CL Childers et al. J Comp Physiol B. 2019 Jan 10
* Mattice JJL. Regulation of glutathione-based antioxidant defenses in response to dehydration stress in the African clawed frog, Xenopus laevis. Thesis 2018
* Alban C et al. Uncovering the protein lysine and arginine methylation network in Arabidopsis chloroplasts. PLoS One. 2014 Apr 18 :9(4):e95512. WB, plants
* Abboud J and Storey KB. Novel control of lactate dehydrogenase from the freeze tolerant wood frog: role of posttranslational modifications. PeerJ 2013 1:e12: WB
* Duong F. et al. Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A. Gastroenterology. 2004 Jan:126(1):263-77.
* Ong S.E. et al. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nat Methods. 2004 Nov:1(2):119-26.
* Mowen K.A. et al. Arginine Methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell. (2004), Nov 24, 119(5),587-590.
* Fabbrizio E. et al. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nat Methods. 2004 Nov:1(2):119-26.
* Li H. et al. Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase. J Biol Chem. 2002 Nov 22:277(47):44623-30.
* Rho J. and al. The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1. J Virol. 2001 Sep:75(17):8031-44.
* Zhu W. et al. Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase. J Biol Chem. 2002 Sep 27:277(39):35787-90.
Covalab提供超過(guò)15000種產(chǎn)品,包括抗體和試劑盒。擁有多種針對(duì)流行和罕見靶標(biāo)的一抗,涉及多種應(yīng)用領(lǐng)域,如癌癥,表觀遺傳學(xué),細(xì)胞信號(hào)傳導(dǎo),心血管等疾病的生物標(biāo)志物,神經(jīng)系統(tǒng),離子通道,微生物學(xué),病毒學(xué)等。還提供特色的應(yīng)用于模式動(dòng)物斑馬魚的抗體。此外還提供ELISA試劑盒,ELISPot試劑盒,F(xiàn)luoroSpot試劑盒等。作為Covalab在中國(guó)的區(qū)域總代理,艾美捷科技有限公司將為中國(guó)客戶提供全面的Covalab產(chǎn)品。
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