相信各位科研er對于CiteAb并不陌生，CiteAb是全球著名的抗體，蛋白，試劑盒搜索引擎，所有產(chǎn)品檢索結(jié)果全部按照文獻(xiàn)引用數(shù)量進(jìn)行排名，產(chǎn)品供貨商無法用付費(fèi)來提升排名，確保產(chǎn)品排名完全公開透明。

近期，CiteAb發(fā)布了關(guān)于2020年全球引用文獻(xiàn)最多的100款試劑盒的調(diào)查報告，定睛一看發(fā)現(xiàn)我們代理的這款超氧化物歧化酶（SOD）檢測試劑盒赫然在列，心想，這么好的試劑盒不讓大家知道真是太可惜啦，今天就給大家介紹下SOD以及這款2021年引文數(shù)量全球第一的SOD檢測試劑盒吧！

（報告詳情：https://blog.citeab.com/which-were-the-top-100-kits-and-assays-of-2020/）

（這款報告是基于全球市場超過700000種試劑盒和超過150000次引用進(jìn)行整理的。）

超氧化物歧化酶（SOD）：

超氧化物歧化酶又稱超氧歧化酶。是一類能催化超氧陰離子自由基(O₂^-)歧化為H₂O₂和O₂的酶。此酶分布極為廣泛，迄今已從細(xì)菌、真菌、藻類、植物、原生動物、昆蟲、魚類和哺乳動物等各種生物體內(nèi)分離到。

超氧歧化酶十分穩(wěn)定，牛紅細(xì)胞SOD在75℃下加熱數(shù)分鐘仍很少失活，對酸堿也較穩(wěn)定，可在pH 5.3～10.5范圍內(nèi)反應(yīng)。

SOD的分類：

超氧歧化酶是一類金屬酶，可分為三種類型：

• 第一種含銅和鋅，稱含銅、鋅超氧歧化酶，呈藍(lán)綠色，主要存在于真核細(xì)胞的細(xì)胞質(zhì)中；

• 第二種含錳，稱含錳超氧歧化酶，呈紫色，主要存在于原核細(xì)胞及真核細(xì)胞的基質(zhì)(如線粒體等)中；

• 第三種含鐵，稱含鐵超氧歧化酶，呈黃褐色，主要存在于原核細(xì)胞及少數(shù)植物細(xì)胞中。

SOD能夠催化超氧陰離子自由基歧化生成氧和過氧化氫，在機(jī)體氧化與抗氧化平衡中起到至關(guān)重要的作用，與很多疾病的發(fā)生、發(fā)展密不可分，因此SOD成為了許多生理過程的重要標(biāo)志物，檢測準(zhǔn)確檢測樣本中SOD的量顯得尤為重要了。

今天給大家?guī)淼倪@款艾美捷科技代理的美國開曼生物公司生產(chǎn)的超氧化物歧化酶（SOD）檢測試劑盒（706002），是經(jīng)過CiteAb權(quán)威驗(yàn)證的，被眾多研究人員信賴并選擇的一款SOD檢測試劑盒（2020年引文數(shù)量全球第一）

超氧化物歧化酶（SOD）檢測試劑盒檢測原理：

優(yōu)勢特點(diǎn)：

樣本類型：血清，血漿，紅和細(xì)胞裂解液，組織勻漿，細(xì)胞裂解液，線粒體

精確度：組內(nèi)CV：3.2%，組間CV：3.7%

檢測范圍：0.005-0.05 units/ml（一個unit定義：50%超氧自由基歧化所需的酶量。）

檢測SOD的類型：可檢測所有三種類型SOD（Cu/Zn、Mn和FeSOD）

測試過的干擾物質(zhì)：

部分引用文獻(xiàn)賞析：

1.Ouyang, B., Li, Z., Ji, X., et al. The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway. Pharm. Biol. 57(1), 529-535 (2019).

2.Wiecek, M., Szymura, J., Maciejczyk, M., et al. Anaerobic Exercise-Induced Activation of Antioxidant Enzymes in the Blood of Women and Men. Front. Physiol. 9, 1006 (2018).

3.Chang, C.-W., Chen, C.-Y., Yen, C.-C., et al. Repressed exercise-induced hepcidin levels after danggui buxue tang supplementation in male recreational Nutrients 10(9), E1318 (2018).

4.Wen, J.J., and Garg, N.J. Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease. PLoS Negl. Trop. Dis. 12(7), e0006687 (2018).

5.Lee, H.Y., Kim, S.W., Lee, G.H., et al. Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress. Sci. Rep. 7(1), 6513 (2017).

6.Wang, M.-Y., Srinivasan, M., Dasari, D., et al. Antioxidant activity of Yichun Blue Honeysuckle (YBHS) berry counteracts CCl4-Induced toxicity in liver injury model of Antioxidants 6(3), 50 (2017).

7.Lee, G.-H., Lee, H.-Y., Choi, M.-K., et al. Protective effect of Curcuma longa L. extract on CCl4-induced acute hepatic stress. BMC Res. Notes 10(1), 77 (2017).

8.Alarifi, S., Ali, H., Alkahtani, S., et al. Regulation of apoptosis through bcl-2/bax proteins expression and DNA damage by nano-sized gadolinium oxide. Int. J. Nanomedicine 12, 4541-4551 (2017).

9.Velviranli, M., Okudan, N., Revan, S., et al. Repeated supramaximal exercise-induced oxidative stress: Effect of β-alanine plus creatine supplementation. Asian J. Sports Med. 7(1), e26843 (2016).

10.Yoon, S.P., and Kim, J. Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity. Anat. Cell Biol. 49, 165-176 (2016).

11.Salvi, A., Patki, G., Khan, E., et al. Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men. Oxid. Med. Cell. Longev. 5059043 (2016).

12.Kleniewska, P., Hoffmann, A., Pniewska, E., et al. The influence of probiotic Lactobacillus casei in combination with prebiotic inulin on the antioxidant capacity of human plasma. Oxid. Med. Cell. Longev. 1340903, (2016).

13.Wang, X.X., Edelstein, M.H., Gafter, U., et al. G protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes. J. Am. Soc. Nephrol. 27(5), 1362-1378 (2016).

14.Adeyemi, K.D., Shittu, R.M., Sabow, A.B., et al. Influence of diet and postmortem ageing on oxidative stability of lipids, myoglobin and myofibrillar proteins and quality attributes of Gluteus Medius muscle in goats. PLOS One 11(5), e0154603 (2016).

15.Vitti, A., Pellegrini, E., Nali, C., et al. Trichoderma harzianum T-22 induces systemic resistance in tomato infected by Cucumber mosaic virus. Front. Plant Sci. 7(1520), (2016).

16.Adeyemi, K.D., Shittu, R.M., Sabow, A.B., et al. Comparison of myofibrillar protein degradation, antioxidant profile, fatty acids, metmyoglobin reducing activity, physicochemical properties and sensory attributes of gluteus medius and infraspinatus muscles in goats. J. Anim. Sci. Technol. 58(23), (2016).

17.Dove, R.E., Leong-Smith, P., Roos-Engstrand, E., et al. Cigarette smoke-induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD. Eur. Clin. Respir. J. 2, (2015).

18.Albaayit, S.F., Abba, Y., Rasdee, A., et al. Effect of Clausena excavata Burm. f. (Rutaceae) leaf extract on wound healing and antioxidant activity in rats. Drug Des. Devel. Ther. 13:9, 3507-3518 (2015).

19.Rouhollahi, E., Moghadamtousi, S.Z., Hakiaghaalipour, F., et al. Curcuma purpurascens BI. rhizome accelerates rat excisional wound healing: involvement of Hsp70/Bax proteins, antioxidant defense, and angiogenesis activity. Drug Des. Devel. Ther. 9, 5805-5813 (2015).

20.Karthivashan, G., Arulselvan, P., Alimon, A.R., et al. Competing role of bioactive constituents in Moringa oleifera extract and conventional nutrition feed on the performance of Cobb 500 broilers. Biomed Res. Int. 970398, (2015).

21.Albaayit, S.F., Abba, Y., Rasedee, A., et al. Effect of Clausena excavata Burm. f. (Rutaceae) leaf extract on wound healing and antioxidant activity in rats. Drug Des. Devel. Ther. 9, 3507-3518 (2015).

22.Almerich-Silla, J.M., Montiel-Company, J.M., Pastor, S., et al. Oxidative stress parameters in saliva and its association with periodontal disease and types of bacteria. Dis. Markers 653537 (2015).

23.Christensen, L.L., Selman, C., Blount, J.D., et al. Plasma markers of oxidative stress are uncorrelated in a wild mammal. Ecol. Evol. 5(21), 5096-5108 (2015).

24.Kadir, F.A., Kassim, N.M., Abdulla, M.A., et al. PASS-predicted hepatoprotective activity of Caesalpinia sappan in thioacetamide-induced liver fibrosis in rats. Sci. World J. 301879 (2014).

25.Dhall, S., Do, D.C., Garcia, M., et al. Generating and reversing chronic wounds in diabetic mice by manipulating wound redox parameters. J. Diabetes Res. 562625, (2014).

26.González-Pe a, D., Angulo, J.F., Vallejo, S., et al. High-cholesterol diet enriched with onion affects endothelium-dependent relaxation and NADPH oxidase activity in mesenteric microvessels from Wistar rats. Nutr. Metab. (Lond) 11:57, (2014).

27.Faisal, M., Saquib, Q., Alatar, A.A., et al. Phytotoxic hazards of NiO-nanoparticles in tomato: A study on mechanism of cell death. J. Hazard. Mater. 250-251, 318-332 (2013).

28.Guo, C.H., Chen, P.C., Hsu, G.S., et al. Zinc supplementation alters plasma aluminum and selenium status of patients undergoing dialysis: A pilot study. Nutrients 5(4), 1456-1470 (2013).

29.Eberle, C., Merki, E., Yamashita, T., et al. Maternal immunization affects in utero programming of insulin resistance and type 2 diabetes. PLoS One 7(9), e45361 (2012).

30.Yuan, C.Y., Lee, Y.J., and Hsu, G.S. Aluminum overload increases oxidative stress in four functional brain areas of neonatal rats. J. Biomed. Sci. 19, 51 (2012).

31.Liu, I.M., Tzeng, T.F., Liou, S.S., et al. Beneficial effect of traditional chinese medicinal formula danggui-shaoyao-san on advanced glycation end-product-mediated renal injury in streptozotocin-diabetic rats. Evid. Based Complement. Alternat. Med. 2012, 140103 (2012).

32.Sullivan-Gunn, M.J., Campbell-O'Sullivan, S.P., Tisdale, M.J., et al. Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle. J. Cachexia Sarcopenia Muscle 2(3), 181-188 (2011).

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