HSP40 is a member of heat shock proteins (HSPs) which are synthesized in cells in response to heat shock and other metabolic stresses and provide a transient state of thermotolerance. HSP40 is localized faintly throughout the cell in non-heat-shocked cells and accumulates in the nuclei and nucleoli in heat-shocked cells (1). The intracellular localization of HSP40 is very similar to that of HSP70. Overexpression of HSP40 reduces aggregate formation and suppresses apoptosis in a neuronal cell model of spinal and bulbar muscular atrophy (inherited neurodegenerative diseases caused by polyglutamine expansion) (2). HSP40 is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Cancer, Cellular Stress, and Inflammation research.
序列
該【干冰】HSP40 recombinant protein-GST fusion protein - 009-001-E57S的詳細信息查看Rockland提供的產品說明書。
來源宿主
該【干冰】HSP40 recombinant protein-GST fusion protein - 009-001-E57S的詳細信息查看Rockland提供的產品說明書。
溶解建議
該【干冰】HSP40 recombinant protein-GST fusion protein - 009-001-E57S的詳細信息查看Rockland提供的產品說明書。
保存建議
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
