【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S-【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein

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中文名稱: 【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S

英文名字: 【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S

背景資料: 14-3-3α/β is a member of the highly conserved 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins (1). 14-3-3α/β protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. 14-3-3-β interacts with the TSC1-TSC2 dimer (2). The interaction required phosphorylation of TSC2 at Ser1210. Binding of 14-3-3-β to TSC2 did not alter the interaction between TSC1 and TSC2, but it reduced the ability of the complex to inhibit phosphorylation of ribosomal protein S6 kinase impairing the ability of the complex to inhibit cell growth. 14-3-3 alpha/beta Protein is ideal for investigators involved in Cell Stress & Chaperone Proteins, Cell Signaling, Cancer research, Cell Cycle, Cellular Stress, Neurobiology, and WNT Signaling research.

序列: 該【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】14-3-3 alpha/beta recombinant protein-GST fusion protein - 009-001-R23S的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。