【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S-【干冰】I kappaB alpha recombinant protein-GST fusion protein

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中文名稱: 【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S

英文名字: 【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S

背景資料: IkB-alpha is an inhibitor of the NFkB complex and inactivates the NFkB by trapping it in the cytoplasm (1). Phosphorylation of serine residues on the IkB protein by IkB kinases (IKKs) marks it for destruction via the ubiquitination pathway, thereby allowing the activation of the NFkB complex. Synthetic glucocorticoid such as dexamethasone display anti-inflammatory effects by inducing the increased synthesis of the IkB protein thereby inhibiting the activity of the NFkB complex. Overexpression of the IkB-alpha gene in fibroblasts leads to inhibition of production of IL-6, TNF receptor, MMP-1, MMP-3 and MMP-13 (2). IkB-alpha Protein is ideal for investigators involved in Signaling Proteins, Transcription Proteins, AKT/PKB Pathway, Apoptosis/Autophagy, Inflammation, and p38 Pathway research.

序列: 該【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】I kappaB alpha recombinant protein-GST fusion protein - 009-001-S17S的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。