IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. The exposure of HeLa cells or human embryonic kidney cells overexpressing IL1R to IL1 caused rapid association of IRAK with the IL1R complex and phosphorylation of IRAK (1).IRAK1is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus (2). IRAK1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Inflammation, NfkB Pathway, p38 Pathway, and Ser/Thr Kinases research.
序列
該【干冰】IRAK1 recombinant protein-GST fusion protein - 009-001-S22的詳細信息查看Rockland提供的產品說明書。
來源宿主
該【干冰】IRAK1 recombinant protein-GST fusion protein - 009-001-S22的詳細信息查看Rockland提供的產品說明書。
溶解建議
該【干冰】IRAK1 recombinant protein-GST fusion protein - 009-001-S22的詳細信息查看Rockland提供的產品說明書。
保存建議
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
