【干冰】PFKFB3 recombinant protein-GST fusion protein - 009-001-S88S-【干冰】PFKFB3 recombinant protein-GST fusion protein

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背景資料: PFKFB3 or 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 is a potent activator of a key regulatory enzyme in the glycolysis pathway called phosphofructokinase. Phosphofructokinase regulates the steady-state concentration of fructose-2, 6-bisphosphate, a potent activator of key regulatory enzyme of the glycolysis pathway. PFKFB3 is bifunctional, although the phosphatase activity is low due to a mutation in an active site which can be upregulated after phosphorylation by protein kinases (1). PFKFB3 may be responsible for sustaining the high glycolytic flux of rapidly proliferating leukemia cells and may represent a molecular target for chemotherapeutic intervention (2). PFKFB3 Protein is ideal for investigators involved in Signaling Proteins, Fructose Kinase Proteins, Cancer, Cell Cycle, and Metabolic Disorder research.

序列: 該【干冰】PFKFB3 recombinant protein-GST fusion protein - 009-001-S88S的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】PFKFB3 recombinant protein-GST fusion protein - 009-001-S88S的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】PFKFB3 recombinant protein-GST fusion protein - 009-001-S88S的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。