【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90-【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein

PRODUCT CENTER

重組蛋白

產品中心

當前位置：首頁 > 產品中心 > 細胞生物學產品 > 重組蛋白

中文名稱: 【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90

英文名字: 【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90

背景資料: PFTK1, also known as PFTAIRE protein kinase 1, is a member of the CDC2 -related protein kinase family which is expressed primarily in the postnatal and adult nervous system (1). PFTK1 is highly expressed in brain, pancreas, kidney, heart, testis, and ovary. PFTK1 interacts with 14-3-3-beta, 14-3-3-epsilon, 14-3-3-eta and 14-3-3-tau. Using PFTK1 mutant constructs and in vitro and in vivo binding studies, it was shown that PFTK1 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms. (2). Significant upregulation of PFTK1 expression is observed in esophageal squamous cell carcinoma (ESCC). PFTK1 is not only useful as a prognostic marker in ESCC, but also as a predictor of the response to chemotherapy. PFTK1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, Cell Cycle, and Ser/Thr Kinases research.

序列: 該【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。