【干冰】VAV1 recombinant protein-GST fusion protein - 009-001-U55-【干冰】VAV1 recombinant protein-GST fusion protein

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背景資料: VAV1 is a member of the VAV gene family which are guanine nucleotide exchange factors (GEFs) for Rho family GTPases. VAV1 activates pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. VAV1 is important in hematopoiesis, playing a role in T-cell and B-cell development and activation (1). VAV1 has been identified as the specific binding partner of Nef proteins from HIV-1. Co-expression and binding of Nef with VAV1 initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.VAV1 proto-oncogene participates in the signaling processes that mediate the antigen-induced activation of B lymphocytes (2). VAV1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, ERK/MAPK Pathway, JNK/SAPK Pathway, and p38 Pathway research.

序列: 該【干冰】VAV1 recombinant protein-GST fusion protein - 009-001-U55的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】VAV1 recombinant protein-GST fusion protein - 009-001-U55的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】VAV1 recombinant protein-GST fusion protein - 009-001-U55的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。