【干冰】VRK3 recombinant protein-GST fusion protein - 009-001-U58S-【干冰】VRK3 recombinant protein-GST fusion protein

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背景資料: VRK3 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases which has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. Profound changes to the active site region underlie the loss of catalytic activity of VRK3 since it cannot bind ATP because of residue substitutions in the binding pocket (1). VRK3 is widely expressed in human tissues and the protein localizes to the nucleus. VRK3 regulates several transcription factors, nuclear envelope assembly, and chromatin condensation and is also required for cell cycle progression (2). VRK3 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, JNK/SAPK Pathway, p38 Pathway, and Ser/Thr Kinases research.

序列: 該【干冰】VRK3 recombinant protein-GST fusion protein - 009-001-U58S的詳細信息查看Rockland提供的產品說明書。

來源宿主: 該【干冰】VRK3 recombinant protein-GST fusion protein - 009-001-U58S的詳細信息查看Rockland提供的產品說明書。

溶解建議: 該【干冰】VRK3 recombinant protein-GST fusion protein - 009-001-U58S的詳細信息查看Rockland提供的產品說明書。

保存建議: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。