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中文名稱

抗PINK1多克隆抗體

英文名字
PINK1 Polyclonal Antibody
供應商
Cayman
產品貨號
10006283-500
產品報價
¥3206/500 μl
產品說明書
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背景資料
Phosphatase and Tensin Homolog -PTEN) dephosphorylates lipids such as phosphatidylinositol 3,4,5-triphosphate -PIP3) and its defects contribute to a variety of human cancers. PTEN induced putative kinase 1 -PINK1) was first identified when studying the tumor-suppressive function of the PTEN signaling pathway and is thus believed to be involved in human cancer pathology. The mRNA of PINK1 is expressed ubiquitously among adult tissues with most abundant expression in the heart, skeletal muscle, and testis. PINK1 is located in mitochondria and its homozygous C-terminus mutation is associated with early onset of Parkinson s disease. Cayman s PINK1 polyclonal antibody recognizes primarily the full length protein at about 66 kDa in human, mouse, and rat tissues. In addition, a truncated form of the protein at about 33 kDa is also detected.
應用類型
WB and IHC -formalin-fixed paraffin-embedded sections); other applications not tested
免疫原
human PINK1 amino acids 484-504 -LVRALLQREASKRPSARVAAN)
來源宿主
rabbit
反應性
Human PINK1+|Mouse PINK1+|Rat PINK1+|
保存建議
其他
Cayman Chemical
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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