- 中文名稱
PtdIns-(4)-P1結合蛋白 (50 ug)
- 英文名字
- PtdIns-(4)-P1 Binding Protein (50 ug)
- 供應商
- Cayman
- 產品貨號
- 10009241-50
- 產品報價
- ￥2450/50 ug
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Pleckstrin homology -PH) domains all contain a seven-standard .beta.-sandwich that allows binding to various species of phosphatidyl inositol -PtdIns) phosphates. Most PH domains bind to phosphatidylinositol phosphates -PIPs) with weak affinity and low specificity, however, a small subclass does bind specifically and with high-affinity for certain PIPs. PtdIns--4)-P1 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns--4)-P1. PIPs represent a small percentage of total membrane phospholipids however, they play a critical role in the generation and transmission of cellular signals. PtdIns--4)-P1 can phosphorylated by kinases to give bi- and triphosphates such as PtdIns--4,5)-P2 and PtdIns--3,4,5)-P3. Phosphorylation of PtdIns--4)-P1 by phosphoinositide -PI)3-kinase to make PtdIns--3,4)-P2 initiates an intricate signalling cascade that has been implicated in cancer.
- 序列
- 來源宿主
- 溶解建議
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
