- 中文名稱
N- [4- [5-（1,3-3-苯并二惡唑-5-基）-3-甲氧基-1H-1,2,4-三唑- 1- [基]苯基] -2-（苯硫基）乙酰胺
- 英文名字
- N-?[4-?[5-?(1,?3-?benzodioxol-?5-?yl)?-?3-?methoxy-?1H-?1,?2,?4-?triazol-?1-?yl]?phenyl]?-?2-?(phenylthio)?-acetamide
- 供應商
- Cayman Chemical
- 產品貨號
- 10009570-25
- 產品報價
- ￥詢價/25mg
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Cytohesins are small guanine nucleotide exchange factors (GEFs) that stimulate adenosine diphosphate ribosylation factors (Arfs), GTPases which control signal transduction along various intracellular pathways.{25737} SecinH3 is a selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50 values of 2.4 to 5.6 μM.{14565} It binds the Sec7 domain of these small Arf-GEFs but does not bind Sec7 domains of larger Arf-GEFs.{25739} In human liver carcinoma HepG2 cells, SecinH3 prevents cytohesin-dependent insulin signaling.{14565} In mice, SecinH3 produces hepatic insulin resistance.{14565} Inhibition of the cytohesin GEF from Drosophila, Steppke, blocks insulin signaling and interferes with development.{25736} SecinH3 is useful for studying the diverse roles of cytohesins, including the regulation of receptor-mediated cancer cell proliferation.{25738}
- 產品描述
- A selective inhibitor of cytohesins, blocking human, mouse, and Drosophila cytohesins with IC50 values of 2.4 to 5.6 μM; prevents cytohesin-dependent insulin signaling in HepG2 cells; produces hepatic insulin resistance in mice
- 產品形式
- A crystalline solid
- 保存建議
- 建議您在收到Cayman Chemical品牌的SecinH3 (25 mg)產品后置于-20度保存，產品有效期為730天.
- 其他
- Cayman Chemical向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.Cayman Chemical可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為Cayman Chemical在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Cayman Chemical產品以及客戶訂制化服務.
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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