The MLL complex methylates histone 3 at lysine 4 (H3K4) to upregulate transcription. MLL1 is the catalytic subunit which exhibits a low basal methyltransferase activity. Addition of WDR5, Ash2L, and RbBP5 (WAR) enhances Histone H3K4 methylation 300-fold;
產品描述
提供的MLL1/WAR復合物(人源重組蛋白)(100 ug)產品形式為:Four tubes containing protein sufficient to form an equimolar ratio of the MLL1/WAR complex
產品形式
The MLL complex methylates histone 3 at lysine 4 ??H3K4?? to upregulate transcription. MLL1 is the catalytic subunit which exhibits a low basal methyltransferase activity. Addition of WDR5?? Ash2L?? and RbBP5 ??WAR?? enhances Histone H3K4 methylation 300-fold??