HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS). The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.
應用類型
FC (QC tested)
免疫原
Papain solubilised HLA-A2, B7
來源宿主
小鼠
反應性
Non-human primates, Human
保存建議
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
