Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
應用類型
FC (QC tested), IP, IHC(P), IHC(F), ICC
免疫原
purified granules from human YT lymphoma cell line
來源宿主
小鼠
反應性
Human, Cow
保存建議
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
