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中文名稱

1,2-二月桂酰-sn-甘油-3-磷酸甘油(Na +鹽)

英文名字
1,2-Dilauroyl-sn-glycero-3-phosphorylglycerol (Na+ salt)
供應商
Matreya
產品貨號
1443-100
產品報價
¥詢價/100mg
產品說明書
點擊查看
購買方式
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產品新聞
背景資料
This product is a high purity, well-defined phosphorylglycerol acylated with lauric acid, making it useful as a standard and for biological studies.1 Phosphorylglycerols are found in pulmonary surfactants, the lipoprotein complex that is formed by type II alveolar cells in the lung. They are important in spreading secreted surfactants over the type I alveolar cells. A decreased level of phosphorylglycerol in cystic fibrosis respiratory mucus is partly responsible for its marked adhesiveness and stickiness, which impairs mucus transport, and distearoyl phosphorylglycerol (DSPG) has been shown to be the most efficient form of phosphorylglycerol in the enhancement of respiratory mucus clearance. The enzyme cardiolipin synthase attaches two phosphorylglycerols together to form cardiolipid which is a major component of the mitochondrial inner membrane.2 Phosphorylglycerol is the main component of some bacterial membranes where it contains diacyl, alkylacyl, or alkenylacyl groups. Phosphorylglycerols generally have saturated and monoenoic fatty acids on position sn-2 and polyunsaturated fatty acids in position sn-1. This is the opposite of the other animal phospholipids and is due to its being synthesized by a different mechanism. Phosphorylglycerol has been found to be essential for the development of thylakoid membranes in some plants.3 Besides being critical in membranes it is essential for the oligomerization of photosystems I and II in cyanobacteria, for the sensitivity to chilling in plants, and for cellular fission and division in bacteria. DSPG has a high transition temperature and has therefore found much use in liposomal drug delivery systems.4 Amphotericin B, an antifungal drug, exhibits significant toxicity towards host cells. Studies using phosphorylglycerol have shown that interactions between amphotericin B and this phospholipid reduces its toxicity towards host cells.5
產品描述
DLPG
產品形式
該1,2-二月桂酰-sn-甘油-3-磷酸甘油(Na +鹽)產品為固體形式
保存建議
對于本產品,我們推薦使用-20℃藍冰低溫進行運輸。在您收到貨物后,我們建議在-20℃溫度下冷凍保存,溶解使用說明請參考本品說明書。
其他
Matreya LLC是一家脂質生化公司,致力于開發和制造高質量的脂質和生物化學品。Matreya在化學合成以及天然產物提取和純化方面經驗豐富,生產出的產品具有最佳純度。 Matreya產品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構體(生育酚和生育三烯酚)。專長是生產高純度鞘氨醇、神經酰胺、硫酸酯、神經節苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質產品最全的供應商之一。產品涉及生物化學、制藥、微生物學、食品和農業等研究領域。
注意
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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