中文名稱

I-RTX；4-羥基-3-碘-5-甲氧基-[（2S，6aR，10R，11aR）-3aR，3bS，6,6a，9aR，10,11,11a-八氫-6a-羥基-8,10-二甲基-11a-（1-甲基乙烯基）-7-氧-2-（苯基甲基）-7H-2,9bR-環氧azuleno [5,4-e] -1,3-苯并二惡唑-5-基]甲酯

英文名字

I-RTX; 4-hydroxy-3-iodo-5-methoxy-[(2S,6aR,10R,11aR)-3aR,3bS,6,6a,9aR,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9bR-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]methyl ester

供應商

Cayman Chemical

產品貨號

15367-1

產品報價

￥已停產

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Resiniferatoxin (Item No. 11349) is a natural analog of capsaicin (Item No. 92350) that activates the transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1.{24790} 5'-Iodoresinferatoxin (I-RTX) is a potent and reversible antagonist of TrpV1 (Kd = 4.3 nM).{24900} However, it can also act as a partial TRPV1 agonist at higher concentrations in vitro, inducing a biphasic response with EC50 values of 56.7 nM and 9.9 μM.{24899} I-RTX blocks activation of TRPV1 by capsaicin both in vitro and in vivo.{24900,24901,24896} It also blocks neurogenic pain induced by inflammatory mediators.{24897,24898}

產品描述

A potent and reversible antagonist of TRPV1 (Kd = 4.3 nM); can also act as a partial TRPV1 agonist at higher concentrations in vitro, inducing a biphasic response with EC50 values of 56.7 nM and 9.9 μM; blocks activation of TRPV1 by capsaicin and pain induced by inflammatory mediators

產品形式

A white to off-white solid

保存建議

建議您在收到Cayman Chemical品牌的5'-Iodoresiniferatoxin (1 mg)產品后置于-20度保存，產品有效期為180天.

其他

Cayman Chemical向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.Cayman Chemical可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為Cayman Chemical在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Cayman Chemical產品以及客戶訂制化服務.

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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