中文名稱

人纖維蛋白原 (PAD2環)（1mg）

英文名字

Human Fibrinogen (PAD2 Citrullinated)

供應商

Cayman Chemical

產品貨號

18473-1

產品報價

￥詢價/1mg

產品說明書

點擊查看

購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868.

產品新聞

背景資料

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (α, β and r). Under chronic inflammatory conditions, fibrinogen can be acted upon by the peptidylarginine deiminases enzymes (PAD2 and PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis (RA) produce antibodies that bind citrullinated human fibrinogen.{21644} The citrullinated fibrinogen and reactive antibodies form immune complexes in RA patients, and these immune complexes can stimulate macrophages.{21645,21643} Immunizing certain strains of mice with citrullinated human fibrinogen can induce the production of anti-citrullinated human fibrinogen antibodies and the development of arthritis that shares many pathophysiological features of the human disease.{21646,21647}

產品描述

Source:Purified from human plasma, citrullinated with human recombinant PAD2 ? MW: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9k Da), and,isoform r-B chain (51.5 kDa)

產品形式

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (??, ?? and r). Under chronic inflammatory conditions, fibrinogen can be acted upon by the peptidylarginine deiminases enzymes (PAD2 and PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis (RA) produce antibodies that bind citrullinated human fibrinogen.{21644} The citrullinated fibrinogen and reactive antibodies form immune complexes in RA patients, and these immune complexes can stimulate macrophages.{21645,21643} Immunizing certain strains of mice with citrullinated human fibrinogen can induce the production of anti-citrullinated human fibrinogen antibodies and the development of arthritis that shares many pathophysiological features of the human disease.{21646,21647}

保存建議

建議收到產品后-80℃保存，避免反復凍融

其他

Cayman Chemical向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.Cayman Chemical可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為Cayman Chemical在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Cayman Chemical產品以及客戶訂制化服務.

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

分享到：