Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Lymphocyte Peyer′s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer′s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
應用類型
FC (QC tested)
免疫原
TK1 cells
來源宿主
大鼠
反應性
Mouse
保存建議
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
