MEK1 antibodies detect the MEK1 isoform. ?Mitogen-activated protein kinase kinase 1, also known as MKK or MEK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ? This pathway also plays a key role in synaptic plasticity in the brain. ?Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. ? MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. ? The MEK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
應用類型
ELISA,Western Blot,
免疫原
Anti-MEK1 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH.
來源宿主
Mouse
反應性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建議
Store vial at 4° C prior to restoration. ? For extended storage aliquot contents and freeze at -20° C or below. ?Avoid cycles of freezing and thawing. ?Centrifuge product if not completely clear after standing at room temperature. ?This product is stable for several weeks at 4° C as an undiluted liquid. ?Dilute only prior to immediate use.
