【干冰】Anti-Nur77 (RABBIT) Antibody - 200-401-H99-【干冰】Anti-Nur77 (RABBIT) Antibody - 200-401-H99代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: Anti Nur7 antibody detects human Nur77. Nur77 (Nak-1,TR3) is a member of the NR4A orphan nuclear receptor (NR) superfamily of transcription factors. The Nur77 ligand has not yet been identified. It is thought that the lack of ability to identify a ligand may be due to the lack of a typical NR binding pocket in the ligand binding domain. Nur77, like other NR4A receptors, are immediate-early genes induced by diverse stimuli in multiple tissues. There is increasing evidence that Nur77 and other NR4A receptors play important roles in maintaining tissue homeostasis. For example, specific Nur77 functions have been defined in the brain, T-cells/thymocytes, adipose tissue, steroidgenesis, muscle, blood vessels, macrophages and cardiovascular system. There is also evidence that Nur77 plays roles in pathological processes such as cancer. Nur77 is a phosphoprotein and its size ranges from ~65 kDa to 90 kDa depending on the isoform expressed and level of phosphorylation or other post-translational modifications. Anti-Nur77 antibody is ideal for investigators involved in apoptosis.

免疫原: Nur77 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to internal amino acids with human Nur77 protein.

保存建議: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。