【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Chicken) Antibody - 200-901-D60-【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Chicken) Antibody

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中文名稱: 【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Chicken) Antibody - 200-901-D60

英文名字: 【干冰】Anti-Glial Fibrillary Acidic Protein (GFAP) (Chicken) Antibody - 200-901-D60

背景資料: GFAP Antibody detects GFAP. Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers.nTherefore, GFAP antibody is ideal for investigators involved in neuropathologic diseases and more generally in Neuroscience.

免疫原: Anti-GFAP Antibody was produced by repeated immunizations with recombinant and extensively purified bovine GFAP.

保存建議: Store vial at -20° C prior to opening.? This product is stable at 4° C as an undiluted liquid.? For extended storage, aliquot contents and freeze at -20° C or below.? Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗體原產企業，其位于美國費城郊區的農場保有近20種實驗動物。Rockland公司為生命科學領域提供豐富的、高質量的抗體，包括載脂蛋白、細胞周期/凋亡、細胞因子、細胞信號蛋白、酶類、細胞外基質、轉錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標記二抗，應用十分廣泛。