IL-1 beta (also known as Interleukin-1 beta, IL-1? and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1? is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. Anti-IL- beta antibody is ideal for investigators involved in Cardiovascular and Immunology research.
應用類型
ELISA,Western Blot,
免疫原
This antibody was prepared by repeated immunizations with recombinant human IL-1? produced in E.coli.? The MW of the recombinant 153 aa IL-1? was 17 kDa with the N-terminal amino acid at position alanine 117.? This cleavage site is generated by the IL-1? converting enzyme (ICE, capase-1).
來源宿主
Rabbit
反應性
Canine (Dog); H. sapiens (Human); Primate
保存建議
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
