- 中文名稱
pCAF Inhibitor Screening BioAssay Kit (Fluorometric) (P300, CBP-Associated Factor, EC 2.3.1.48, K (Lysine) Acetyltransferase 2B, KAT2B)
- 英文名字
- pCAF Inhibitor Screening BioAssay Kit (Fluorometric) (P300, CBP-Associated Factor, EC 2.3.1.48, K (Lysine) Acetyltransferase 2B, KAT2B)
- 供應商
- USBiological
- 產品貨號
- 220132
- 產品報價
- ￥1/100Tests
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- USBiological品牌是全球有名的抗原抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區域總代理，是行業中少有的致力于服務客戶，幫助客戶，且擁有獨立的專業銷售團隊、技術支持團隊、市場營銷團隊、進出口報關團隊的高科技生物企業。可以為您提供及時的咨詢響應，專業的產品和解決方案支持，穩健快捷的交貨周期，優質放心的售后服務。我們致力于為您提供有價值的產品和服務，在意您的成功！
- 產品描述
- pCAF (P300/CBP-associated factor, EC 2.3.1.48) also known as K (lysine) acetyltransferase 2B (KAT2B), possesses intrinsic histone acetyltransferase (HAT) activity. pCAF contributes to transcriptional activation by acetylating chromatin and transcription factors through its HAT activity. Deregulated HAT activity plays an important role in various cancers. pCAF inhibitors have potential applications in cancer therapy. pCAF uses both histone 3 (H3) and histone 4 (H4) as substrates.Intended Use:For screening, studying and characterizing potential inhibitors of pCAF.Test Principle:The pCAF Inhibitor Screening BioAssay Kit utilizes H3 peptide and Acetyl CoA as the substrates. pCAF acetylates the peptide and generates Coenzyme A with a free thiol group. The CoA is detected using a Thiol Detecting Probe that reacts with thiol groups and gives enhanced fluorescence that can be measured at Ex/Em = 392/482nm. In the presence of pCAF specific inhibitors, the enzymatic activity is inhibited resulting in decreased or total loss of fluorescence. This assay kit is a simple, sensitive, and rapid tool to screen potential pCAF inhibitors.Kit Components:pCAF Assay Buffer, 1x20ml ?pCAF Enzyme, 1x40ul ?Acetyl CoA, lyophilized, 1x vial ?H3 Peptide, lyophilized, 1x vial ?Thiol Detecting Probe, 1x200ul ?pCAF Inhibitor (Garcinol), 1x10ul Storage and Stability:Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 產品特點
- 針對pCAF Inhibitor Screening BioAssay Kit (Fluorometric) (P300, CBP-Associated Factor, EC 2.3.1.48, K (Lysine) Acetyltransferase 2B, KAT2B)該產品的特點優勢，歡迎查閱官網提供的產品說明書。
- 保存建議
- 建議收到pCAF Inhibitor Screening BioAssay Kit (Fluorometric) (P300, CBP-Associated Factor, EC 2.3.1.48, K (Lysine) Acetyltransferase 2B, KAT2B)產品后將其置于-20°C保存。
- 其他
- Usbiological公司是美國著名的抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。Usbiological公司現已擁有超過50,19234種抗體、抗原和生化產品，為科研用戶提供了諸多超值選擇。
-
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
