Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-5 is also known as Ich-3 and ICErel-III and can proteolytically processed by granzyme B. Over expression of caspase-5 induces apoptosis in Rat-1 and HeLa cells，which can be inhibited by CrmA and Bcl-2.
應用類型
Western blotting （0.5-4ag/ml）. However， the optimal conditions should be determined individually. The affinity purified antibody preferentially detects the intermediate （32 kDa） and the fully （20 kDa） cleaved caspase-5.
免疫原
Synthetic peptide surrounding amino acids 162 of human caspase-5
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠、猴、倉鼠、牛種屬來源的Caspase-5蛋白發生免疫反應.
保存建議
提供的Caspase-5抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Caspase-5抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
