MBD4 （methyl-CpG-binding domain protein 4） belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2，MBD1，MBD2，and MBD4，except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis.
應用類型
The antibody can be used in Western Blot analysis （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 474 of mouse MBD4
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的MBD4蛋白發生免疫反應
保存建議
提供的100 ug MBD4抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該MBD4抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
