c-FLIP was cloned by several labs independently and termed Casper，I-FLICE，FLAME-1，CASH AND CLARP. c-FLIP contains two death effector domains and has sequence homology to caspase-8. c-FLIP interacts with adapter protein FADD and caspaser-8 and -10，and potently inhibits apoptosis induced by all known death receptors. Two splice variants of c-FLIP have been identified and termed FLIPl and FLIPs
應用類型
Western blot analysis （0.5-4 ug/ml） and immunofluorescence. However， the optimal conditions should be determined individually. The immunoaffinity-purified antibody detects 58 kDa FLIPL on SDS-PAGE immunoblots， in samples from human， mouse and rat origins. The antibody recognizes only the FLIPL form.
免疫原
Synthetic peptide near the C-terminus of human FLIPa/FLIPL form
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的c-FLIP蛋白發生免疫反應.
保存建議
提供的c-FLIP抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該c-FLIP抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
