Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact，granzyme B is directionally exocytosed and assisted by perforin，enters the target cell. With its unique substrate specificity （granzyme B cleaves after Asp），granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.
應用類型
Western blot， Immunoprecipitation， Immunohistochemistry， flow cytometry. However， the optimal conditions should be determined individually.
免疫原
Human recombinant Granzyme B （a.a. 7-227）
來源宿主
小鼠
反應性
經檢測驗證，可與人種屬來源的Granzyme B 蛋白 發生免疫反應.
保存建議
提供的Granzyme B 抗體 產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Granzyme B 抗體 產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
