This antibody reacts with the Stage-specific embryonic antigen-4 (SSEA-4) that is expressed upon the surface of human teratocarcinoma stem cells (EC),human embryonic germ (EG) cells) and human embryonic stem (ES) cells. No immunoreactivity is evident with undifferentiated murine EC,ES and EG cells. Expression of SSEA-4 is down-regulated following differentiation of human EC cells. In contrast,the differentiation of murine EC and ES cells may be accompanied by an increase in SSEA-4 expression.
應用類型
Flow (cell Surface), IHC, IP, Western Blot
免疫原
Human embryonal carcinoma cell line 2102Ep
來源宿主
小鼠
反應性
經檢測驗證,可與人種屬來源的SSEA-4蛋白發生免疫反應.
保存建議
提供的SSEA-4抗體產品為25 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有0.05% BSA和0.05% 疊氮鈉的PBS緩沖液中.請將該SSEA-4抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.