Cytochrome P450 is mainly found in liver,and can metabolize a wide range of compounds such as organic solvents,acetaminophen,dimethylnitrosoamine and aliphatic alcohol,which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.
應用類型
Western blotting (0.5-4 ug/ml) .However, the optimal conditions should be determined individually. The antibody detects ~58kDa cytochrome P450 IIE1 from samples of human, mouse, rat and dog origins.
免疫原
Synthetic peptide surrounding amino acid 405 of human Cytochrome p450
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠、狗種屬來源的Cytochrome P450蛋白發生免疫反應.
保存建議
提供的Cytochrome P450抗體產品為100 ug 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該Cytochrome P450抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.