Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT6 catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. PRMT6 has been shown to act as a restriction factor for HIV replication.
應用類型
Western Blot analysis (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3086BP-50) is available separately.
免疫原
Synthetic peptide surrounding amino acid 361 of rat PRMT6
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的PRMT6蛋白發生免疫反應
保存建議
提供的100 ug PRMT6抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該PRMT6抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.