TCTN1 belongs to the Tectonic protein family that regulate Hedgehog （Hh） pathway. During neural tube development，TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. At later stages in development，TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
應用類型
Western Blot analysis （0.5-4 ug/ml）. It detects 64 kDa TCTN1 and its cleavage fragment. However， the optimal concentrations should be determined individually. Blocking peptide （Cat.# 3087BP-50） is available separately.
免疫原
Synthetic peptide surrounding amino acid 520 of rat TCTN1
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的TCTN1蛋白發生免疫反應
保存建議
提供的100 ug TCTN1抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該TCTN1抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
