Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play important roles in determining tissue specific cell fate during embryogenesis,like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5’ CANNTG 3’.Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.
應用類型
Western Blot analysis (1 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3090BP-50) is available separately.
免疫原
Synthetic peptide surrounding amino acid 556 of rat TCF3/E2A
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的TCF3/E2A蛋白發生免疫反應
保存建議
提供的100 ug TCF3/E2A抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該TCF3/E2A抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.