Proinsulin is a prohormone precursor to Insulin，made by the pancreas in response to increased blood sugar. Proinsulin is 39 amino acids longer than the mature Insulin，of which 4 are completely lost and the remaining 35 forms the C-peptide. The measurement of Proinsulin in serum provides a useful，valuable information for the diagnosis of insulinomas. Proinsulin levels have also been shown to be elevated in non-insulin dependent diabetics （NIDDM），in insulin dependent diabetics （IDDM） and other clinical situations. The antibody recognizes insulin and recombinant proinsulin，but does not react with synthetic C-peptide.
應用類型
The antibody can be used for indirect ELISA， WB and IHC.
免疫原
Recombinant full length insulin
來源宿主
小鼠
反應性
經檢測驗證，可與人、牛、豬種屬來源的ProInsulin蛋白發生免疫反應.
保存建議
提供的ProInsulin抗體產品為100 ug 無色溶液，其濃度為1.0 mg/ml，溶解于包含有0.05% （W/V） 疊氮鈉的PBS緩沖液中.請將該ProInsulin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
