AMPK （PRKAA1） belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase （AMPK）. AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
應用類型
The antibody can be used for ELISA （0.25 ug/ml）， Western blotting （2.5 – 5.0 ug/ml） and Immunohistochemistry （5 -25 ug/ml）.
免疫原
Synthetic peptide corresponding to the amino acid residues surrounding S487 of human PRKAA1
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的AMPK蛋白發生免疫反應.
保存建議
提供的AMPK抗體產品為100 ug 無色溶液，其濃度為0.25 mg/ml，溶解于包含有0.09% （W/V） 疊氮鈉的PBS緩沖液中.請將該AMPK抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
