HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes,including hepatocyte nuclear factor 1 alpha,a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver,kidney,and intestines. Mutations in the HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
應用類型
The antibody can be used for ELISA (0.25 ug/ml) and Western blotting (2.5 – 5.0 ug/ml).
免疫原
Synthetic peptide selected from the center region of human HNF4A
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的HNF4A蛋白發生免疫反應.
保存建議
提供的HNF4A抗體產品為100 ug 無色溶液,其濃度為0.25 mg/ml,溶解于包含有0.09% (W/V) 疊氮鈉的PBS緩沖液中.請將該HNF4A抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.