MAK10 protein regulates the proliferation of smooth muscle cells. The mammalian homologue of yeast MAK10，also known as EGAP，is one subunit of a novel N-terminal acetyltransferase （NAT） that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult，remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development.
應用類型
Western blotting （2-4 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 201 of rat MAK10
來源宿主
兔
反應性
經檢測驗證，可與人、大鼠種屬來源的MAK10蛋白發生免疫反應
保存建議
提供的100 ug MAK10抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該MAK10抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
