Protein kinases are enzymes that transfer a phosphate group from a phosphate donor，generally the g phosphate of ATP，onto an acceptor amino acid in a substrate protein. By this basic mechanism，protein kinases mediate most of the signal transduction in eukaryotic cells，regulating cellular metabolism，transcription，cell cycle progression，cytoskeletal rearrangement and cell movement，apoptosis，and differentiation. With more than 500 gene products，the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine （PTK） or serine/threonine （STK） kinase catalytic domains.
應用類型
The antibody can be used for ELISA （0.25 ug/ml） and Immunohistochemistry （2.5 – 5.0 ug/ml）.
免疫原
Synthetic peptide selected from the N-terminal region of human PI3KB
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的PI3KB蛋白發生免疫反應.
保存建議
提供的PI3KB抗體產品為100 ug 無色溶液，其濃度為0.25 mg/ml，溶解于包含有0.09% （W/V） 疊氮鈉的PBS緩沖液中.請將該PI3KB抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
