AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore,AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
應用類型
The antibody can be used for ELISA (0.25 ug/ml) and Western Blotting (0.5 – 2.5 ug/ml).
免疫原
Synthetic peptide selected from the C-terminal region of human Akt2
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的Akt2蛋白發生免疫反應.
保存建議
提供的Akt2抗體產品為100 ug 無色溶液,其濃度為0.25 mg/ml,溶解于包含有0.09% (W/V) 疊氮鈉的PBS緩沖液中.請將該Akt2抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.