NANOG is a transcription regulator involved with inner cell mass and embryonic stem （ES） cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extra-embryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.
應用類型
The antibody can be used for ELISA （0.25 ug/ml） and Western Blotting （2.5 – 5.0 ug/ml）.
免疫原
His fusion recombinant protein of human FOXP3
來源宿主
兔
反應性
經檢測驗證，可與人 種屬來源的Nanog蛋白發生免疫反應.
保存建議
提供的Nanog抗體產品為100 ug 無色溶液，其濃度為0.25 mg/ml，溶解于包含有0.09% （W/V） 疊氮鈉的PBS緩沖液中.請將該Nanog抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
