SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins,such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
應用類型
The antibody can be used for ELISA (0.25 ug/ml) and Western Blotting (2.5 – 5.0 ug/ml).
免疫原
Synthetic peptide selected from the N-terminal region of human SOX4
來源宿主
兔
反應性
經檢測驗證,可與人種屬來源的SOX4蛋白發生免疫反應.
保存建議
提供的SOX4抗體產品為100 ug 無色溶液,其濃度為0.25 mg/ml,溶解于包含有0.09% (W/V) 疊氮鈉的PBS緩沖液中.請將該SOX4抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融.