Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers，but undetectable in terminally differentiated adult tissues. It has been shown that recombinant expression of Survivin counteracts apoptosis of B lymphocyte precursors deprived of interleukin 3 （IL-3），suggesting a potential role of Survivin in cancer therapy. Survivin is expressed in G2-M phase in a cell cycle-dependent manner and directly associated with mitotic spindle microtubules，suggesting a role in both apoptosis regulation and cell cycle progression.
應用類型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
Recombinant human survivin
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的Survivin蛋白發生免疫反應
保存建議
提供的100 ug Survivin抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Survivin抗體產品置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.
