The precursor of cytochrome c，apocytochrome c，is synthesized in the cytoplasm. Upon translocation into mitochondria，cytochrome c acquires a heme moiety required for functionality in the mitochondrial respiration chain. The heme-bound form of cytochrome c is called holocytochrome c. When released into the cytosol，cytochrome c can activate caspases responsible for apoptosis.
應用類型
Western blot analysis （5-10 ug/ml） and immunoprecipitation. The antibody detects a 12.0 kDa protein corresponding to the apparent molecular weight of cytochrome c.
免疫原
Cytochrome c purified from human heart
來源宿主
小鼠
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Holocytochrome c蛋白發生免疫反應.
保存建議
提供的Holocytochrome c抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02% 疊氮鈉的PBS緩沖液中.請將該Holocytochrome c抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
