Human perforin （cytolysin） is believed to be one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. Perforin expression is constitutive on NK cells，but increases in resting XD8+ cytotoxic cells upon activation.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects ~70 kDa Perforin in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 568 of rat Perforin
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Perforin蛋白發生免疫反應.
保存建議
提供的Perforin抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Perforin抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
