AIF （apoptosis inducing factor） was recently identified that causes chromatin condensation and DNA fragmentation. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation，which are the hallmarks of apoptosis. AIF is highly conserved between human and mouse and widely expressed.
應用類型
Western blotting （0.5-4 ug/ml）. A ~67 kDa band should be detected. Jurkat cell lysate can be used as a positive control. However， the optimal conditions for your testing samples should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 520 of human AIF
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的AIF蛋白發生免疫反應.
保存建議
提供的AIF抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該AIF抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
