BAFF （for B cell Activating Factor） is a novel member in the TNF family. BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNF- and TRAIL，THANK was shown to activate NF-kB and c-Jun N-terminal kinase （JNK） and to induce apoptosis.
應用類型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. A 32 kDa full length BAFF and the 18 kDa cleavage fragment can be detected.
免疫原
Recombinant human BAFF
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的BAFF蛋白發生免疫反應.
保存建議
提供的BAFF抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該BAFF抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
