NAIP （neuronal apoptosis inhibitor protein） is a member of the IAPs （inhibitor of apoptosis proteins） that function in cell death pathways to inhibit apoptosis. NAIP was discovered based on its association with a neurodegenerative disorder. Mutations and deletions in the NAIP gene locus is a contributing factor in spinal muscular atrophy. Coexpression of NAIP and hippocalcin protects neurons against calcium-induced cell death. NAIP is strongly expressed in anterior horn and motor cortex neurons of the normal brain. It is also found in human fetal neurons and in adult choroid plexus cells.
應用類型
The antibody detects recombinant human NAIP in extracts from Sf21 insect cells by Western blot analysis （0.5-4 ug/ml）.
免疫原
Synthetic peptide surrounding amino acid 506 of human NAIP
來源宿主
兔
反應性
經檢測驗證，可與人種屬來源的NAIP蛋白發生免疫反應.
保存建議
提供的NAIP抗體產品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該NAIP抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
