Enhancer of zeste homolog 2 (Ezh2) is a member of the Polycomb group (PcG). The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity,cell cycle regulation,and oncogenesis. Enhancer of zeste homolog 2 (Ezh2) contains four conserved regions including domain I,domain II,and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis.
應用類型
Western Blot analysis (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3242BP-50) is available separately.
免疫原
Synthetic peptide mapping to the N-terminus of rat Ezh2
來源宿主
兔
反應性
經檢測驗證,可與人、小鼠、大鼠種屬來源的EZH2蛋白發生免疫反應
保存建議
提供的100 ug EZH2抗體產品為無色溶液其濃度為0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中.請將該EZH2抗體產品置于-20 °C冷凍保存,建議分裝使用以避免反復凍融.