G16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of G16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-B and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of G15，a mouse orthologue of human G16，causes reduced C5 receptor signaling. G16 serves as a marker，in addition to CD34，for hematopoietic progenitor cells.
應用類型
Western blotting （0.5-4 ug/ml） and in Immunohistochemistry （5-20 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects G15 in samples from human， mouse， rat， and rabbit origins. It also detects G16 from samples of human origin. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 356of human G 15
來源宿主
兔
反應性
經檢測驗證，可與人、小鼠、大鼠種屬來源的Ga15/16蛋白發生免疫反應.
保存建議
提供的Ga15/16抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）緩沖液中.請將該Ga15/16抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
